✯✯✯ CC-501: A Case Study

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CC-501: A Case Study

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Case study: setting the problem (Antonio Ghezzi)

The number of non eye-related adverse events reported within six months post-implantation. The total number of severe adverse events reported from Day 1 post-implantation through study completion at Year 3. The total number of eye-related adverse events reported from Day 1 post-implantation through study completion at Year 3. The total number of non eye-related adverse events reported from Day 1 post-implantation through study completion at Year 3.

Hardy Rand Rittler testing followed the guidelines accompanying the test and administered under a Macbeth Lamp at lux. Eligibility Criteria. Inclusion Criteria: To be eligible, the following inclusion criteria must be met, where applicable. Participant must be 18 years of age or older. Participant must understand and sign the protocol informed consent. Both female participants of childbearing potential and male participants able to father children must have or have a partner who has had a hysterectomy or vasectomy, be completely abstinent from intercourse, or must agree to use contraception during the first six months following implantation.

Acceptable forms of contraception include:hormonal contraception i. Exclusion Criteria: A participant is not eligible if any of the following exclusion criteria are present. Participant has a history of other ocular disease likely to contribute significantly to visual loss e. Participant is judged by the investigator as not sufficiently healthy to safely undergo ophthalmic surgery.

Participant is on anticoagulant therapy that cannot be safely stopped peri-operatively at the implant procedure. Patients on warfarin will always be excluded. Patients on aspirin will be asked to stop the medication at least seven days prior to the surgery when not contraindicated by the underlying medical condition. The stoppage period for other anticoagulant medications is based on the best clinical judgment of the investigator surgeon and is variable depending on the patient's medical condition and the type of medication. Participant has had diagnosis or treatment of a malignancy excluding non-melanoma skin cancer within the previous five years.

Participant has received investigational treatment in another clinical study related to an ocular condition in the last six months. Participant is pregnant, lactating or planning to become pregnant in the first six months following implantation. Study Eye Eligibility Criteria: The participant must have at least one eye meeting all inclusion criteria and none of the exclusion criteria listed below. Study Eye Exclusion Criteria: The study eye has a choroidal nevus or ocular neoplasm with potential risk for malignant transformation.

The study eye is judged by the investigator, based on history or examination findings, as high-risk for retinal detachment, vitreous hemorrhage, infection, or uveitis. The study eye has lens, cornea, or other media opacities precluding adequate visualization and testing of the retina. The study eye has undergone intraocular surgery within 12 months prior to enrollment. Study Eye Selection Criteria in Cases of Bilateral Disease: As this is a genetic condition that usually affects both eyes to a similar degree, if both eyes of a participant meet the study eye eligibility criteria and have comparable visual acuity, the study eye will be selected at the investigator's medical judgment after consultation with the participant.

In case of an eye with lower visual acuity, that eye will be selected as the study eye. Contacts and Locations. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials. More Information. Invest Ophthalmol Vis Sci. Hum Mol Genet. CNGA3 mutations in hereditary cone photoreceptor disorders.

Am J Hum Genet. Epub Aug View Article Google Scholar 3. Observation of practices at petting zoos and the potential impact on zoonotic disease transmission. Clinical Infectious Diseases. Animal—visitor interactions in the modern zoo: Conflicts and interventions. Applied Animal Behaviour Science. View Article Google Scholar 5. Hosey GR. Zoo animals and their human audiences: what is the visitor effect?. Animal Welfare. View Article Google Scholar 6. Serrell B. The evolution of educational graphics in zoos. Environment and Behavior. View Article Google Scholar 7. Controlling public feeding of zoo animals. Visitor Behavior. View Article Google Scholar 8. The effects of involvement on responses to argument quantity and quality: Central and peripheral routes to persuasion.

Journal of Personality and Social Psychology. View Article Google Scholar 9. Capraro V, Vanzo A Understanding moral preferences using sentiment analysis. Managing social norms for persuasive impact. Social Influence. View Article Google Scholar Umphrey LR. The effects of message framing and message processing on testicular self-examination attitudes and perceived susceptibility. Communication Research Reports. Meyerowitz BE, Chaiken S. The effect of message framing on breast self-examination attitudes, intentions, and behavior. Kim NY. The influence of message framing and issue involvement on promoting abandoned animals adoption behaviors. Procedia-Social and Behavioral Sciences. Davis JJ. The effects of message framing on response to environmental communications.

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Faraway J. Linear models with R. Taylor SM. Featured Client Monastery of Christ in the Desert This job began with designing a new website and logo for this Benedictine monastery. More work samples and case studies. More blog posts. Personal Projects I make websites and inventions that let me explore my obsessions: I like fooling with electronics, cryptocurrency, music-making, and gathering together communities of people with similar interests. SampleSwap SampleSwap. More personal projects, including some pretty weird stuff.

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